Methods for assessing the cumulative effect of multiple factors on the manifestation of the effect in biomedical research
Abstract
In biomedical research, it is often necessary to quantitatively assess the combined effect of multiple factors-both quantitative and qualitative-on a specific biomedical outcome. This article discusses approaches to data normalization, determination of factor weights, information aggregation, and model development for evaluating the cumulative influence of factors. Both expert-based and data-driven methods are examined, along with their application to health prediction, risk assessment, and decision-making in biomedicine.
About the Authors
Z. B. Sabirov
NC JSC «National Centre Occupational Health and Diseases»
Kazakhstan
Kazakhstan
PhD, Head of the Scientific Laboratory of Occupational Pathology
100017, Karaganda, Mustafina str. 15, e-mail: info@naoncgt.kz
E. Z. Otarov
NC JSC «National Centre Occupational Health and Diseases»
Kazakhstan
Kazakhstan
100017, Karaganda, Mustafina str. 15, e-mail: info@naoncgt.kz
A. V. Alekseev
NC JSC «National Centre Occupational Health and Diseases»
Kazakhstan
Kazakhstan
100017, Karaganda, Mustafina str. 15, e-mail: info@naoncgt.kz
O. V. Grebeneva
NC JSC «National Centre Occupational Health and Diseases»
Kazakhstan
Kazakhstan
100017, Karaganda, Mustafina str. 15, e-mail: info@naoncgt.kz
A. Z. Shadetova
NC JSC «National Centre Occupational Health and Diseases»
Kazakhstan
Kazakhstan
100017, Karaganda, Mustafina str. 15, e-mail: info@naoncgt.kz
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Review
For citations:
Sabirov Z.B., Otarov E.Z., Alekseev A.V., Grebeneva O.V., Shadetova A.Z. Methods for assessing the cumulative effect of multiple factors on the manifestation of the effect in biomedical research. Occupational Hygiene and Medical Ecology. 2025;(3):9-17.
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