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The role of nasopharyngeal microbiota in the development of ENT diseases

Abstract

The article explores the role of the nasopharyngeal microbiota in the development of ENT diseases. It describes the composition of the normal microbiota and its influence on the immune response of the body. The consequences of dysbiosis are examined, including an increased risk of infections such as sinusitis, otitis, and tonsillitis. The impact of antibiotics on the microbiota is discussed, as well as potential strategies for restoring its balance using probiotics. The importance of studying the nasopharyngeal microbiota for the prevention and treatment of ENT diseases is emphasized, along with the need for further research in this area.

About the Authors

V. V. Aksenov
State Municipal Enterprise on the Right of Economic Management "Multidisciplinary Regional Hospital" of the Municipal Public Institution "Health Department of the Akimat of North Kazakhstan Region"
Kazakhstan

otolaryngologist of the highest category 

150010, Region, Petropavlovsk, 123 Vasiliev Street, e-mail: gz-ob_sko@mail.ru



S. I. Bedesheva
Khoja Akhmet Yassawi International Kazakh-Turkish University
Kazakhstan

161200, Turkistan, 29 Bekzat Sattarkhanov Street, e-mail: info@ayu.edu.kz



K. E. Abilov
Khoja Akhmet Yassawi International Kazakh-Turkish University
Kazakhstan

161200, Turkistan, 29 Bekzat Sattarkhanov Street, e-mail: info@ayu.edu.kz



A. S. Kozhabekova
Khoja Akhmet Yassawi International Kazakh-Turkish University
Kazakhstan

161200, Turkistan, 29 Bekzat Sattarkhanov Street, e-mail: info@ayu.edu.kz



References

1. Brook, I. (2019). The Role of Nasopharyngeal Bacterial Flora in Chronic Respiratory Infections. Journal of Clinical Microbiology, 57(7), 88-101. https://doi.org/10.1128/JCM.00111-19.

2. Tsai, T. Y., et al. (2020). Antibiotic resistance in nasopharyngeal microbiota: Implications for the treatment of chronic upper respiratory tract infections. Microbial Drug Resistance, 26(4), 451-459. https://doi.org/10.1089/mdr.2019.0331.

3. Biesbroek, G., et al. (2017). Role of the Microbiota in Chronic Rhinosinusitis. Clinical Microbiology Reviews, 30(2), 384-399. https://doi.org/10.1128/CMR.00018-16.

4. O’Brien, K. L., et al. (2017). The Role of Nasopharyngeal Microbiota in Pneumococcal Carriage and Disease. PLOS Pathogens, 13(9), e1006530. https://doi.org/10.1371/journal.ppat.1006530.

5. Chonmaitree, T., et al. (2015). Microbial Interactions in the Nasopharynx and Otitis Media in Children. The Pediatric Infectious Disease Journal, 34(1), 103-109. https://doi.org/10.1097/INF.0000000000000500.

6. Tsolia, M., et al. (2016). Upper Respiratory Tract Infection and the Nasopharyngeal Microbiome in Children. The Journal of Pediatrics, 179, 174-179. https://doi.org/10.1016/j.jpeds.2016.08.010.

7. Pires, D., et al. (2020). Dysbiosis of Nasopharyngeal Microbiota and Antibiotic Resistance in Patients with Chronic Sinusitis.Microorganisms, 8(11), 1742. https://doi.org/10.3390/microorganisms8111742.

8. Murphy, T. F., et al. (2018). The Microbiome of the Nasopharynx and Its Role in Upper Respiratory Tract Infections. European Journal of Clinical Microbiology & Infectious Diseases, 37(5), 779-789. https://doi.org/10.1007/s10096-018-3414-9.

9. van der Sluijs, M. F., et al. (2017). Nasopharyngeal Microbiota and Its Association with Acute Respiratory Infections in Children.Scientific Reports, 7, 8760.https://doi.org/10.1038/s41598-017-09377-w.

10. Wyllie, A. L., et al. (2020). Characterization of Nasopharyngeal Microbiota in Adults with Acute Otitis Media. Ear, Nose & Throat Journal, 99(7), 459-467. https://doi.org/10.1177/0145561319897224.


Review

For citations:


Aksenov V.V., Bedesheva S.I., Abilov K.E., Kozhabekova A.S. The role of nasopharyngeal microbiota in the development of ENT diseases. Occupational Hygiene and Medical Ecology. 2025;(3):67-76. (In Russ.)

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ISSN 1727-9712 (Print)