Toxicological assessment of drilling fluids and drilling muds: development of hazard and safety criteria for human health and the environment

An experimental study was conducted to assess the toxicological properties of the drilling fluid, including its general toxic, local irritant, and dermal-resorptive effects. Clinical and behavioral parameters, food and water consumption, body weight dynamics, relative weights of internal organs, and hematological and biochemical blood parameters were evaluated. The results obtained characterize the combined systemic and local toxic effects of the investigated drilling fluid.

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